ノバルティスのインスタグラム(novartis) - 4月1日 16時30分

Like crafty matchmakers, molecular glues stick proteins together inside cells. By doing so, they may change a cell’s destiny.
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First discovered in plants, molecular glues were created by nature. Some plant defense mechanisms, such as antibiotics, work by sticking proteins together. This idea of interrupting disease by bringing two proteins together is relatively new in human drug discovery.
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Our drug hunters think these tiny matchmakers have the potential to change the course of diseases that are difficult to treat, like cancer. Our researchers are taking a systematic approach to discovering glues that have the potential to alter disease-driving biology. Because molecular glues work differently from traditional small molecule drugs, they open the door to potentially discovering new kinds of medicines.

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