ノバルティスのインスタグラム(novartis) - 4月10日 09時00分
A new wave of therapies is unleashing the body’s immune system on #cancer, significantly extending lives. These agents, however, don’t work for everyone, so scientists are exploring new approaches that will enable immunotherapies to more effectively combat tumors. One idea, born of a bioengineer, involves loading baby-aspirin-sized scaffolds with immunotherapy agents and inserting them near tumors. These biodegradable scaffolds can potentially serve as “boot camps” for immune cells, recruiting and training them to recognize tumors and launch an attack. Although tumors often release signals that trick the immune system into thinking that everything is okay, the scaffolds could keep such signals at bay, allowing immune cells to devote their full attention to the compounds in their immediate vicinity. Since the scaffolds are porous, once immune cells enter, researchers have control over the microenvironment and can provide them with the right cues while shielding them from systemic signaling. Novartis recently entered a licensing agreement and collaboration with the @WyssInstitute (at @Harvard University) and the @DanaFarber explore the potential applications of this technology. #AACR18
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2018/4/10
